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posted on 20.01.2021, 15:26 authored by Xuewei Li, Nana Ping, Yong Wang, Xiaoyu Xu, Lijuan Gao, Zhao Zeng, Ling Zhang, Zhibo Zhang, Yiyu Xie, Changgeng Ruan, Depei Wu, Zhengming Jin, Suning Chen

Philadelphia chromosome positive (Ph+) in T-lineage acute lymphoproliferative tumors is a rare event in both children and adults. In particular, it has not been reported in T-cell lymphoblastic lymphoma(T-LBL) yet. Here, we describe a patient with Ph+ T-LBL for both cytogenetic abnormality and BCR-ABL1 fusion transcript. Moreover, we review the published cases of Ph+ T-cell acute lymphoblastic leukemia (T-ALL) in the literature and summarize their clinical characteristics, management, and prognosis.

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