Image_2_Delineation of the Feline Hippocampal Formation: A Comparison of Magnetic Resonance Images With Anatomic Slices.JPEG (29.63 kB)
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Image_2_Delineation of the Feline Hippocampal Formation: A Comparison of Magnetic Resonance Images With Anatomic Slices.JPEG

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posted on 08.11.2019, 12:32 by Isabella Gruber, Sibylle Kneissl, Alexander Probst, Akos Pakozdy

The hippocampal formation (HF) is a relevant brain structure that is involved in several neurological and psychiatric diseases. In cats, structural changes of the HF are associated with epilepsy. The knowledge of a detailed anatomy of this brain region may lead to the accurate diagnosis and development of better therapies. There are, however, discrepancies among the research findings, which may be due to different definitions being used, according to anatomical guidelines and boundaries, as well as different magnetic resonance (MR) protocols. The aim of this study is to evaluate the anatomical borders of the HF on transverse MR images and the correlated anatomic sections in three cats. The boundaries of the HF were mostly visible in the formalin fixed anatomic sections, except in the areas where the hippocampus proper exchanges into the subicular complex. Also, the delineation of the anteroventral part and the latero-caudal borders of the HF were not clearly defined. Based on our preliminary results these problems are reinforced on MR images, and further histological and anatomical research must be done to find a way to delineate these neurological structures accurately.

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