Image_1_Abdomen Depth and Rectus Abdominis Thickness Predict Surgical Site Infection in Patients Receiving Elective Radical Resections of Colon Cancer.JPEG (382.16 kB)
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Image_1_Abdomen Depth and Rectus Abdominis Thickness Predict Surgical Site Infection in Patients Receiving Elective Radical Resections of Colon Cancer.JPEG

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posted on 15.07.2019, 13:32 by Song Liu, Meng Wang, Xiaofeng Lu, Min Feng, Feng Wang, Liming Zheng, Wenxian Guan

Background: Surgical site infection (SSI) hampers the advantages of surgical management, which requires early forecast particularly in patients receiving colorectal surgery. This study is to explore potential relationship between individual abdominal anatomic characteristics including subcutaneous fat thickness (SFT), rectus abdominis thickness (RAT), and abdomen depth (AD), with the incidence of SSI in elective radical resection of colon malignancy.

Materials and Methods: This retrospective case-control study has recruited 55 patients in each SSI and non-SSI group with propensity score match method. Demographics, clinical attributes, and pre- and intra-operative information were compared between groups with univariate analysis to elicit significant parameters, which were subsequently brought into logistic regression and receiver-operating characteristic (ROC) analysis.

Results: Patients with SSI showed lower preoperative albumin (p = 0.0022), higher RAT (p = 0.014), AD (p = 0.029), and the multiplied value (RAT × AD) (p = 0.0026) contrasted with patients without SSI. Logistic regression demonstrated RAT × AD as an independent risk factor for SSI (OR = 1.007, p < 0.001) and a biomarker for SSI prediction (AUC = 0.83, 95% CI: 0.74 ~ 0.91).

Conclusions: Preoperative RAT and abdomen depth are associated with the risk of postoperative SSI in patients receiving elective radical resection of colon cancer.

Trial Registration:www.researchregistry.com, identifier researchregistry3669

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