Table_2_Serum Chloride Level Is Associated With Abdominal Aortic Calcification.DOCX (15.85 kB)
Download file

Table_2_Serum Chloride Level Is Associated With Abdominal Aortic Calcification.DOCX

Download (15.85 kB)
dataset
posted on 18.01.2022, 04:29 authored by Sheng Hu, Tian Lan, Silin Wang, Lang Su, Sheng Zou, Jiayue Ye, Yang Zhang, Deyuan Zhang, Qiang Guo, Wenxiong Zhang, Dongliang Yu, Jianjun Xu, Yiping Wei, Jinhua Peng
Background

Abdominal aortic calcification is a potentially important independent risk factor for cardiovascular health. The aim of this study was to determine the relationship between serum chloride level and abdominal artery calcification.

Methods

We obtained the data of 3,018 individuals from the National Health and Nutrition Examination Survey database and analyzed the relationship between serum chloride and abdominal artery calcification. We performed stratified and single factor analysis, multiple equation regression analysis, smooth curve fitting, and threshold effect and saturation effect analysis. R and EmpowerStats were used for data analysis.

Results

Serum chloride is independently related to the AAC total 24 score (AAC-24). The smooth curves fitted were all inverted-U shaped. Below a cutoff value of 92 mmol/L, increase in serum chloride level was associated with increase in AAC-24; however, above that cutoff, increase in serum chloride level was associated with decrease in AAC-24.

Conclusions

At serum levels below 92 mmol/L, chloride is a risk factor for abdominal aortic calcification but levels above 92 mmol/L appear to protect against abdominal aortic calcification.

History