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Table_1_Identification of a Torque Teno Mini Virus (TTMV) in Hodgkin’s Lymphoma Patients.DOCX
At least 12% of human cancers are caused by virus infection. To understand whether other viruses are associated with human cancers, a viral metagenomics approach was used to analyze the composition of the viral communities of the serum of the patients with Hodgkin’s lymphoma (HL) and non-Hodgkin lymphoma. In this report, a human anellovirus TTMV named TTMV-SH was discovered from three patients with HL. The complete genome of TTMV-SH is 2812nt in length. Phylogenetic analysis based on ORF1 indicated that TTMV-SH of the 11 isolates cluster with TTMV strain TLMV-CBD231 sharing only 60.3–62% sequence similarity, and the sequences divergence is 41.5–43.1%, which indicates that TTMV-SH is a novel species. The TTMV-SH prevalence in HL group, especially in nodular sclerosing Hodgkin’s lymphomas (NSHL), was significantly higher than in the healthy group implicated that the TTMV-SH may be associated with HL, especially NSHL.
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References
- https://doi.org//10.1002/jmv.24146
- https://doi.org//10.1073/pnas.211424698
- https://doi.org//10.1007/978-3-540-70972-5_2
- https://doi.org//10.1007/s12032-017-1057-4
- https://doi.org//10.1080/10428190701203954
- https://doi.org//10.1128/JCM.39.5.2022-2024.2001
- https://doi.org//10.1183/09031936.00107212
- https://doi.org//10.1016/j.autrev.2006.03.002
- https://doi.org//10.1080/17474086.2017.1326815
- https://doi.org//10.3389/fonc.2016.00207
- https://doi.org//10.1053/j.semdp.2017.04.003
- https://doi.org//10.1016/j.chom.2014.02.011
- https://doi.org//10.18632/oncotarget.22400
- https://doi.org//10.1073/pnas.77.12.7415
- https://doi.org//10.1016/j.cld.2017.03.006
- https://doi.org//10.1098/rstb.2016.0274
- https://doi.org//10.1007/s00705-015-2363-9
- https://doi.org//10.1007/s11262-017-1505-4
- https://doi.org//10.1038/srep26739