Table_1_Cannabis Use Is Associated With Lower COVID-19 Susceptibility but Poorer Survival.PDF
To investigate the impact of cannabis use on the infection and survival outcomes of COVID-19.
Study DesignCross-sectional study based on the UK Biobank (UKB) dataset.
MethodsWe identified 13,099 individuals with cannabis smoking history in the UKB COVID-19 Serology Study. The Charlson-Quan Comorbidity Index was estimated using inpatient ICD-10 records. Multivariable logistic regression characterized features associated with COVID-19 infection. Cox models determined the hazard ratios (HR) for COVID-19-related survival.
ResultsCannabis users were more likely to getting COVID-19 (odds ratio: 1.22, P = 0.001) but multivariable analysis showed that cannabis use was a protective factor of COVID-19 infection (adjusted odds ratio: 0.81, P = 0.001). Regular cannabis users, who smoked more than once per month, had a significantly poorer COVID-19-related survival, after adjusting for known risk factors including age, gender, smoking history, and comorbidity (adjusted hazard ratio: 2.81, P = 0.041).
ConclusionsThe frequency of cannabis use could be considered as a candidate predictor for mortality risk of COVID-19.
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References
- https://doi.org//10.1016/S1473-3099%2820%2930243-7
- https://doi.org//10.1038/s41586-020-2521-4
- https://doi.org//10.1016/S0140-6736%2816%2900619-X
- https://doi.org//10.1371/journal.pmed.1001779
- https://doi.org//10.1093/aje/kwx246
- https://doi.org//10.1097/01.mlr.0000182534.19832.83
- https://doi.org//10.1038/s41591-020-0962-9
- https://doi.org//10.1056/nejmra1402309
- https://doi.org//10.1111/add.15387
- https://doi.org//10.1097/ADM.0000000000000798
- https://doi.org//10.1093/sleep/zsab138
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