Data_Sheet_1_VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons.PDF (1.83 MB)
Data_Sheet_1_VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons.PDF
dataset
posted on 2018-10-02, 04:44 authored by Christian Wozny, Prateep Beed, Noam Nitzan, Yona Pössnecker, Benjamin R. Rost, Dietmar SchmitzThe subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.
