DataSheet_1_Real-Time Flash Glucose Monitoring Had Better Effects on Daily Glycemic Control Compared With Retrospective Flash Glucose Monitoring in Patients With Type 2 Diabetes on Premix Insulin Therapy.pdf
To compare the effects of real-time and retrospective flash glucose monitoring (FGM) on daily glycemic control and lifestyle in patients with type 2 diabetes on premix insulin therapy.
Methods and ResultsA total of 172 patients using premix insulin, with HbA1c ≥ 7.0% (56 mmol/mol), or the time below the target (TBR) ≥ 4%, or the coefficient of variation (CV) ≥36% during the screening period, were randomly assigned to retrospective FGM (n = 89) or real-time FGM group (n = 83). Another two retrospective or real-time 14-day FGMs were performed respectively, 1 month apart. Both groups received educations and medication adjustment after each FGM. Time in range (3.9~10.0 mmol/l, TIR) increased significantly after 3 months in the real-time FGM group (6.5%) compared with the retrospective FGM group (-1.1%) (p = 0.014). HbA1c decreased in both groups (both p < 0.01). Real-time FGMs increased daily exercise time compared with the retrospective group (p = 0.002).
ConclusionsReal-time FGM with visible blood glucose improves daily glycemic control and diabetes self-care behaviors better than retrospective FGM in patients with type 2 diabetes on premix insulin therapy.
Clinical Trial Registrationhttps://clinicaltrials.gov/NCT04847219.
History
References
- https://doi.org//10.2337/dc20-S005
- https://doi.org//10.1186/2251-6581-12-14
- https://doi.org//10.2337/dc20-S007
- https://doi.org//10.2147/PPA.S57567
- https://doi.org//10.1177/1479164119827456
- https://doi.org//10.1016/S2213-8587(19)30385-7
- https://doi.org//10.1007/s13300-017-0255-6
- https://doi.org//10.1055/a-0994-9850
- https://doi.org//10.1007/s13300-020-00879-x
- https://doi.org//10.1177/1559827619890955
- https://doi.org//10.1186/s12902-015-0044-z
- https://doi.org//10.1111/dom.14365
- https://doi.org//10.1111/dom.14298
- https://doi.org//10.1111/dom.12626
- https://doi.org//10.2337/dci19-0028
- https://doi.org//10.1002/dmrr.3158
- https://doi.org//10.1007/s13300-016-0223-6
- https://doi.org//10.2337/dc18-0166
- https://doi.org//10.1186/s13098-021-00654-3
- https://doi.org//10.1016/j.amjmed.2013.02.035
- https://doi.org//10.1016/j.diabres.2018.04.043
- https://doi.org//10.2337/dc10-1548
- https://doi.org//10.1177/1932296816632241
- https://doi.org//10.1007/s00125-012-2708-9
- https://doi.org//10.2337/dc20-0112
- https://doi.org//10.1111/jdi.12954
- https://doi.org//10.1089/dia.2017.0386
- https://doi.org//10.1016/j.numecd.2017.10.023
- https://doi.org//10.3390/nu13124492
- https://doi.org//10.3390/nu13114162
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