DataSheet1_Actaticas A−G, Cycloartane Triterpenes From Actaea asiatica With Their Antiproliferative Activity.docx (7.42 MB)
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DataSheet1_Actaticas A−G, Cycloartane Triterpenes From Actaea asiatica With Their Antiproliferative Activity.docx

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posted on 29.07.2021, 04:11 by Meigeng Hu, Dan Zhao, Xudong Xu, Guoxu Ma, Haifeng Wu, Xi Chen

Phytochemical studies on the rhizomes of Actaea asiatica led to the isolation of seven new cycloartane triterpenes, actaticas A−G (1−7). Their structures were determined by NMR, HRESIMS, and chemical analysis. All the isolates were evaluated for their antiproliferative activity against HT-29 and McF-7 cell lines. The results showed that all the compounds displayed cytotoxicity. All compounds showed significant inhibitory effects with IC50 values of 9.2–26.4 μM.

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