10.3389/fneur.2019.00969.s001 Ferdinand O. Bohmann Ferdinand O. Bohmann Natalia Kurka Natalia Kurka Richard du Mesnil de Rochemont Richard du Mesnil de Rochemont Katharina Gruber Katharina Gruber Joachim Guenther Joachim Guenther Peter Rostek Peter Rostek Heike Rai Heike Rai Philipp Zickler Philipp Zickler Michael Ertl Michael Ertl Ansgar Berlis Ansgar Berlis Sven Poli Sven Poli Annerose Mengel Annerose Mengel Peter Ringleb Peter Ringleb Simon Nagel Simon Nagel Johannes Pfaff Johannes Pfaff Frank A. Wollenweber Frank A. Wollenweber Lars Kellert Lars Kellert Moriz Herzberg Moriz Herzberg Luzie Koehler Luzie Koehler Karl Georg Haeusler Karl Georg Haeusler Anna Alegiani Anna Alegiani Charlotte Schubert Charlotte Schubert Caspar Brekenfeld Caspar Brekenfeld Christopher E. J. Doppler Christopher E. J. Doppler Oezguer A. Onur Oezguer A. Onur Christoph Kabbasch Christoph Kabbasch Tanja Manser Tanja Manser Waltraud Pfeilschifter Waltraud Pfeilschifter STREAM Trial Investigators STREAM Trial Investigators Table_1_Simulation-Based Training of the Rapid Evaluation and Management of Acute Stroke (STREAM)—A Prospective Single-Arm Multicenter Trial.DOCX Frontiers 2019 CRM thrombolysis (tPA) stroke emergency care simulation training 2019-09-11 04:26:20 Dataset https://frontiersin.figshare.com/articles/dataset/Table_1_Simulation-Based_Training_of_the_Rapid_Evaluation_and_Management_of_Acute_Stroke_STREAM_A_Prospective_Single-Arm_Multicenter_Trial_DOCX/9797150 <p>Introduction: Acute stroke care delivered by interdisciplinary teams is time-sensitive. Simulation-based team training is a promising tool to improve team performance in medical operations. It has the potential to improve process times, team communication, patient safety, and staff satisfaction. We aim to assess whether a multi-level approach consisting of a stringent workflow revision based on peer-to-peer review and 2–3 one-day in situ simulation trainings can improve acute stroke care processing times in high volume neurocenters within a 6 months period.</p><p>Methods and Analysis: The trial is being carried out in a pre-test-post-test design at 7 tertiary care university hospital neurocenters in Germany. The intervention is directed at the interdisciplinary multiprofessional stroke teams. Before and after the intervention, process times of all direct-to-center stroke patients receiving IV thrombolysis (IVT) and/or endovascular therapy (EVT) will be recorded. The primary outcome measure will be the “door-to-needle” time of all consecutive stroke patients directly admitted to the neurocenters who receive IVT. Secondary outcome measures will be intervention-related process times of the fraction of patients undergoing EVT and effects on team communication, perceived patient safety, and staff satisfaction via a staff questionnaire.</p><p>Interventions: We are applying a multi-level intervention in cooperation with three “STREAM multipliers” from each center. First step is a central meeting of the multipliers at the sponsor's institution with the purposes of algorithm review in a peer-to-peer process that is recorded in a protocol and an introduction to the principles of simulation training and debriefing as well as crew resource management and team communication. Thereafter, the multipliers cooperate with the stroke team trainers from the sponsor's institution to plan and execute 2–3 one-day simulation courses in situ in the emergency department and CT room of the trial centers whereupon they receive teaching materials to perpetuate the trainings.</p><p>Clinical Trial Registration: STREAM is a registered trial at https://clinicaltrials.gov/ct2/show/NCT03228251.</p>