10.3389/fneur.2019.00710.s002 Anne-Catherine Bachoud-Lévi Anne-Catherine Bachoud-Lévi Joaquim Ferreira Joaquim Ferreira Renaud Massart Renaud Massart Katia Youssov Katia Youssov Anne Rosser Anne Rosser Monica Busse Monica Busse David Craufurd David Craufurd Ralf Reilmann Ralf Reilmann Giuseppe De Michele Giuseppe De Michele Daniela Rae Daniela Rae Ferdinando Squitieri Ferdinando Squitieri Klaus Seppi Klaus Seppi Charles Perrine Charles Perrine Clarisse Scherer-Gagou Clarisse Scherer-Gagou Olivier Audrey Olivier Audrey Christophe Verny Christophe Verny Jean-Marc Burgunder Jean-Marc Burgunder Table_1_International Guidelines for the Treatment of Huntington's Disease.XLSX Frontiers 2019 Huntington's disease guidelines treatment care clinical practice 2019-07-03 13:48:44 Dataset https://frontiersin.figshare.com/articles/dataset/Table_1_International_Guidelines_for_the_Treatment_of_Huntington_s_Disease_XLSX/8540525 <p>The European Huntington's Disease Network (EHDN) commissioned an international task force to provide global evidence-based recommendations for everyday clinical practice for treatment of Huntington's disease (HD). The objectives of such guidelines are to standardize pharmacological, surgical and non-pharmacological treatment regimen and improve care and quality of life of patients. A formalized consensus method, adapted from the French Health Authority recommendations was used. First, national committees (French and English Experts) reviewed all studies published between 1965 and 2015 included dealing with HD symptoms classified in motor, cognitive, psychiatric, and somatic categories. Quality grades were attributed to these studies based on levels of scientific evidence. Provisional recommendations were formulated based on the strength and the accumulation of scientific evidence available. When evidence was not available, recommendations were framed based on professional agreement. A European Steering committee supervised the writing of the final recommendations through a consensus process involving two rounds of online questionnaire completion with international multidisciplinary HD health professionals. Patients' associations were invited to review the guidelines including the HD symptoms. Two hundred and nineteen statements were retained in the final guidelines. We suggest to use this adapted method associating evidence base–medicine and expert consensus to other rare diseases.</p>