10.3389/fmicb.2018.00258.s003
Qun Li
Qun
Li
Hong Wang
Hong
Wang
Yanmei Xu
Yanmei
Xu
Xiangning Bai
Xiangning
Bai
Jianping Wang
Jianping
Wang
Zhengdong Zhang
Zhengdong
Zhang
Xiang Liu
Xiang
Liu
Yimao Miao
Yimao
Miao
Ling Zhang
Ling
Zhang
Xinqiong Li
Xinqiong
Li
Nianli Zou
Nianli
Zou
Guodong Yan
Guodong
Yan
Xi Chen
Xi
Chen
Jie Zhang
Jie
Zhang
Shanshan Fu
Shanshan
Fu
Ruyue Fan
Ruyue
Fan
Jianguo Xu
Jianguo
Xu
Juan Li
Juan
Li
Yanwen Xiong
Yanwen
Xiong
Table_2.doc
Frontiers
2018
Escherichia albertii
β-lactam
β-lactamases
ESBL
mcr-1
2018-02-16 04:21:19
Dataset
https://frontiersin.figshare.com/articles/dataset/Table_2_doc/5896195
<p>Escherichia albertii is an emerging member of the Enterobacteriaceae causing human and animal enteric infections. Antimicrobial resistance among enteropathogens has been reported to be increasing in the past years. The purpose of this study was to investigate antibiotic resistance and resistance genes in E. albertii isolated from Zigong city, Sichuan province, China. The susceptibility to 21 antimicrobial agents was determined by Kirby–Bauer disk diffusion method. The highest prevalence was tetracycline resistance with a rate of 62.7%, followed by resistance to nalidixic acid and streptomycin with a rate of 56.9 and 51.0%, respectively. All isolates were sensitive or intermediate susceptible to imipenem, meropenem, amoxicillin–clavulanic acid, and levofloxacin. Among 51 E. albertii isolates, 15 were extended-spectrum β-lactamase-producing as confirmed by the double disk test. The main β-lactamase gene groups, i.e., bla<sub>TEM</sub>, bla<sub>SHV</sub>, and bla<sub>CTX-M</sub>, were detected in17, 20, and 22 isolates, respectively. Furthermore, four colistin-resistant isolates with minimum inhibitory concentrations of 8 mg/L were identified. The colistin-resistant isolates all harbored mcr-1 and bla<sub>CTX-M-55</sub>. Genome sequencing showed that E. albertii strain SP140150 carried mcr-1 and bla<sub>CTX-M-55</sub> in two different plasmids. This study provided significant information regarding antibiotic resistance profiles and identified the co-occurrence of β-lactamase and MCR-1 encoding genes in E. albertii isolates.</p>