10.3389/fpls.2019.01507.s001
Michael James Van Oosten
Michael James
Van Oosten
Emilia Dell’Aversana
Emilia
Dell’Aversana
Alessandra Ruggiero
Alessandra
Ruggiero
Valerio Cirillo
Valerio
Cirillo
Yves Gibon
Yves
Gibon
Pasqualina Woodrow
Pasqualina
Woodrow
Albino Maggio
Albino
Maggio
Petronia Carillo
Petronia
Carillo
Table_1_Omeprazole Treatment Enhances Nitrogen Use Efficiency Through Increased Nitrogen Uptake and Assimilation in Corn.docx
Frontiers
2019
benzimidazole
nitrogen use efficiency
proton pump inhibitor
maize
nitrogen assimilation
nitrate reductase
2019-12-04 04:32:17
Dataset
https://frontiersin.figshare.com/articles/dataset/Table_1_Omeprazole_Treatment_Enhances_Nitrogen_Use_Efficiency_Through_Increased_Nitrogen_Uptake_and_Assimilation_in_Corn_docx/11315048
<p>Omeprazole is a selective proton pump inhibitor in humans that inhibits the H<sup>+</sup>/K<sup>+</sup>-ATPase of gastric parietal cells. Omeprazole has been recently shown to act as a plant growth regulator and enhancer of salt stress tolerance. Here, we report that omeprazole treatment in hydroponically grown maize improves nitrogen uptake and assimilation. The presence of micromolar concentrations of omeprazole in the nutrient solution alleviates the chlorosis and growth inhibition induced by low nitrogen availability. Nitrate uptake and assimilation is enhanced in omeprazole treated plants through changes in nitrate reductase activity, primary metabolism, and gene expression. Omeprazole enhances nitrate assimilation through an interaction with nitrate reductase, altering its activation state and affinity for nitrate as a substrate. Omeprazole and its targets represent a novel method for enhancing nitrogen use efficiency in plants.</p>